Research project principal investigator:  Chair Professor Chung-Yu Wu

After the implementation of the project in 2019, we have been able to improve the biocompatible packaging process of the retina chip, deposit the infrared filter layer of the nano-multilayer film on the image sensor, and coat IrOx at the electrode on the artificial retina chip. After the electrode is prepared, the biocompatible packaging material Parylene-C will be coated on the outer layer of the chip, and the biocompatible packaging process research and test verification method of artificial retina chip will be carried out.

The biocompatibility process of the implantable retinal chip has been carried out by the Japanese side. The dies have been completed. The preliminary biological tests have verified that they can stimulate the retina and intercept the VEP signal in the visual cortex of the brain. No lesions in the implantation area were observed. The above results have been published jointly in two international journals and one international conference paper, with fruitful results.

 

≡ After the implementation of the plan in 2019, we will expand from single die technology to 8-inch wafer technology based on IrOx coated electrodes and biocompatible packaging material Parylene-C technology in the laboratory of Professor NAIST Ohta in Japan. Department of innovation and breakthrough technology.

 

≡ Team member Prof. Pu-wei Wu’s PhD student Kuang-Chih Tso went to Prof. Ohta''s laboratory, NAIST, for Joint-PhDs in October 2019. Under the joint guidance of Prof. Pu-wei Wu and Prof. Ohta, he conducts research in the field of biostimulation electrodes and biomedical devices.

 

≡ Prof. Chung-Yu Wu, Prof. Ming-Dou Ker, Prof. Yu-Ting Cheng, Prof. Chen-Yi Lee, PhD student Chi-Kuan Tseng, PhD student Chia-Chi Hsieh, PhD student Kun-Lin Tsou, and PhD student Yi-Huan Ou Yang were invited to participate in NCTU-NAIST Joint Bilateral Symposium. The students made posters based on their experimental results, participated in poster exhibitions, visited the laboratory of the Photonic Device Science Laboratory, and conducted patterned coating experiments on IrOx biocompatible electrodes.