SDGs in ECE NYCU

3D cell printing and neural stimulation microelectrode array technology cooperation

College of Electrical and Computer Engineering 2019/12/30

Research project principal investigator: Professor Ming-Dou Ker

The AIIM Research Center of the University of Wollongong in Australia produced a set of 3D Bio-printing equipment for BETRC. This equipment is used to 3D print retinal cells on the retina chip. BETRC provides a set of electrical stimulation platform equipment for the AIIM research center, which is a multi-channel electrical stimulation and recording system suitable for cell culture and characterization, and arranges researchers and graduate students from both sides to conduct cell electrical stimulation technology research and 3D cell printing experiments, improve the parameters and bio-inks suitable for 3D printing of cells, and build an environment suitable for cell attachment and growth on the retina chip, and adjust the specifications of the 8-channel electrical stimulator module provided by National Chiao Tung University to output the current of the stimulator The specification is adjusted to the tolerable range of electrical stimulation of cells, so that the effects of electrical stimulation and regeneration of stem cells can have better results.

This mutually beneficial cooperation is of great significance. It can enhance the research of both parties, and actually carry out transnational technical cooperation, which is helpful to the technological innovation of implantable medical electronic products.

3D Bio-Printer provided by AIIM Research Center in Wollongong, Australia.

The members of BETRC, Prof. Chung-Yu Wu, Prof. Ming-Dou Ker, Prof. Pu-Wei Wu, Prof. Jui-I Chao, Assistant Professor Kuan-Yu Chen, Research Assistant Jia-wei Yang and PhD student Chong-You Chen went to the University of Wollongong, Australia, on May 4-9, 2019, participating in Joint workshop. The two parties reported the current research progress and had detailed discussions, confirming the direction and implementation details of the next stage of cooperation, and formally signed a memorandum of understanding. During this trip, they also visited the newly expanded 3D biomedical material printing laboratory at the University of Wollongong.

The signing ceremony of the cooperation agreement between the two parties (07/05/2019).

Prof. Gordon Wallace of the University of Wollongong, Australia, invited the project members of BETRC, Prof. Chung-Yu Wu, Prof. Ming-Dou Ker, and Prof. Yu-Ting Cheng to participate in the "Wireless Communication with Biosystems Workshop" on Nov. 11, 2019, and they presented relevant research technologies. The topics of this conference include the development of new technologies such as chip design of biomedical devices, wireless transmission of recorded data, and wireless control of stimulation parameters.

Professor Wu Chongyu, Professor Ke Mingdao and Professor Zheng Yuting were invited to the University of Wollongong to participate Wireless Communication with Biosystems Workshop and give a speech at the conference (2019/11/11).

BETRC invited Prof. Gordon Wallace and Dr. Johnson Chung to visit NCTU on Nov. 19-20, 2019, and held bilateral symposium for communicating with each other. The two parties had in-depth discussions on the topic of 3D Bio-printing and Cell stimulation/Sensing. In addition, the two parties discussed the results of cell printing experiments using the 3D printer provided by UOW, and provided solutions to the problems to facilitate subsequent related experiments.

Prof. Gordon Wallace and Dr. Johnson Chung from University of Wollongong, Australia came to Taiwan Guide the 3D cell printing technology of this project (2019/11/19).