Research project principal investigator:  Professor Guan-Yu Chen

Integrate the Electrical, computer and engineering technology of the National Chiao Tung University team and the scientific research experience of foreign teams. We establish precision diagnosis and treatment evaluation with an organ-on-chips bionic system. Our team has established a Lung-on-a-chip system for health assessment of suspended particulate matter to complete the platform development of the entire air pollution health assessment model. It includes a bionic alveolar experimental model and respiratory simulation system. This novel system can propose corresponding pollutant toxicology, exposure assessment and dose response curve database for lung health risk assessment. Also, the platform can used to explore the health problems caused by fine suspended particles on the human respiratory system (alveolar tissue) for provide favorable clues to bring more directions and possibilities for next drug development and treatment strategies.

The results of the team shined in this year's Ministry of Science and Technology Future Science and Technology Exhibition. The technical achievements won the "Future Science and Technology Breakthrough Award" and the "Best Popular Technology Award". During the 4-day exhibition in December, it attracted thousands of visitors to the booth. Create up to 500 people or more for discussion and exchange. It is worth mentioning that this technology has become a characteristic result of visits by the Minister of Science and Technology, the Secretary-General of the Executive Yuan, the ambassadors abroad and other distinguished guests and many media.