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National Yang Min Chiao Tung University ("NYCU") is a top research university in Taiwan as well as in East Asia. Located close to Hsinchu Science Park (HSP)--the "Silicon Valley" of Taiwan. The College of Electrical and Computer Engineering of NCTU, established in 1994, was the first college in Taiwan focusing on the fields of electrical engineering and computer science. It is ranked as the top among all the engineering colleges in Taiwan. The college also collaborates closely with the industry and initiates numerous joint research projects. Our alumni from the College of ECE have played a significant role within the global industries of information, integrated circuits, networks, and communications, from the Science Park in Hsinchu, Taiwan to Silicon Valley in California, USA.

High-Sensitivity and Trace-Amount Specimen Electrochemical Sensors for Exploring the Levels of β‑Amyloid in Human Blood and Tears

Institute of Biomedical Engineering 2022/07/15

June 8, 2021, Volume 93, Issue 22 Cover
  • GOOD HEALTH AND WELL-BEING

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As the occurrence of Alzheimer’s disease (AD) has increased, the detection and treatment of AD have become global social issues. Effective early detection and wide-range screening of AD allow patients to gain early control and delay brain degeneration. For these reasons, we choose electrochemical sensors to complete the detection task. Although bio-electrochemical technology for antibody and antig...

Breath Ammonia Is a Useful Biomarker Predicting Kidney Function in Chronic Kidney Disease Patients

2022/07/13

The sensing system includes a desiccation cylinder, an airtight sensing chamber, a rotameter, a pump, and an electrical signal measurement instrument (Keysight U2722A USB Modular Source Measure Unit).
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Chronic kidney disease (CKD) is a public health problem and its prevalence has increased worldwide; patients are commonly unaware of the condition. The present study aimed to investigate whether exhaled breath ammonia via vertical-channel organic semiconductor (V-OSC) sensor measurement could be used for rapid CKD screening. We enrolled 121 CKD stage 1–5 patients, including 19 stage 1 patients, 26...

Enhancement in operational current of PTB7 based ammonia gas sensor utilizing F4-TCNQ as P-type dopant

2022/07/13

The PTB7 ammonia sensing element doped with the P-type dopant F4-TCNQ has a nearly two orders higher working current than the undoped element due to the improvement of hole mobility and the reduction of the energy barrier of carrier injection. The current variation of sensing ammonia is also twenty times greater than before doping.
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In recent years, the population of chronic kidney disease (CKD) in the world has increased rapidly due to the coming of aging society. The risk of death and the need of patient care for CKD patients is considerably high, so it is expected that as the number of CKD patients increases, the cost and burden on medical resources will also be inevitably high . Therefore, CKD screening especially for ear...

Developing Flexible PPG Sensor Patch

Institute of Electrical and Control Engineering 2022/07/08

Flexible PPG sensor patch
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We will establish a firm alliance between the Sensors IC Lab by Prof. Chao and all the related companies, including tech manufacturers of Wisechip and Epistar, IN design houses of Weltrend and Pixart, the system and sales compnaies of Inalways, TOYO Pham and Wsitron, etc. We will not only focused on advances of the key technologies on the flexible sensor patch, but also integrate the key know-how...

Development of the PPG blood flow sensor system applied to detect the injury of carotid artery induced by the radiotherapy for headand-neck cancer patients

Institute of Electrical and Control Engineering 2022/07/08

blood flow sensor  system
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Dedicated to detect the carotid stenosis of patients with head and neck cancers. The aforementioned carotid stenosis are often induced by radiotherapy, possibly leading to cerebral ischemia and/or stroke. The MOHW of Taiwan has reported in June 2020 that cancers remains the no. 1 cause of death for 38 years, about 28.6% of the total deaths in the nation and increasing every year. Among all the can...

Multiple Top-Notch Information-Domain Scholars Awarded in Annual Meeting of Institute of Information & Computing Machinery

2022/04/27

Prof. Li-Chun Wang is awarded the K.T. Li Fellow Award by Chi-Chao Wan, the Secretary-general of K. T. Li Foundation Development of Science and Technology. (Photo provided by IICM)
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The Institute of Information & Computing Machinery (IICM) held an annual meeting on 24th April at the Administrative Office in Taipei of National Dong Hwa University (NDHU). The meeting is hosted by Josh Chao, the President of the IICM and the Principle of NDHU. In the meeting, Chao and Chi-Chao Wan, the Secretary-general of K. T. Li Foundation Development of Science and Technology, jointly issue ...

2021 Mobilehero Networked Future Challenge Announces Excellent Works- New Business and Application for Post-Pandemic Era

2021/11/22

PDcare Shoe Pad
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In the 2021 Mobilehero Networked Future Challenge, the judges spend a lot of time reviewing and discussing the works before finally deciding on 22 pieces of work for the final. All chosen pieces of work are presented in an online exhibition that is worth visiting. The exhibition shows various creative products with intelligent network connections. Many authors propose solutions targeting new needs...

Design and realization of ultrasonic sensor readout for evaluating the injury induced by radiotherapy

Institute of Electrical and Control Engineering 2021/08/01

Ultrasonic  sensor
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To develop an novel non-invasive ultrasonic sensor patch and its readout integrated circuit to instantly and accurately monitor neck artery wound caused by radiation therapy. According to the MOHW of Taiwan, cancers account for about 28.6% of the total deaths in the nation and the number is increasing every year, which makes cancers the no. 1 cause of death for consecutive 38 years. One of the mos...

Lung-on-chip with smart health assessment

Institute of Biomedical Engineering 2021/07/13

Inhalation of airborne contaminants and particle penetration are simulated on an in vitro model.
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Prof. Guan-Yu Chen’s team has set up a lung-on-chip system and completed the development of a platform for smart health assessment, inclusive of a bionic alveolar experimental model combining with a human-simulated respiratory system, for air pollution. For the risk assessment of human lung health, not only does this novel platform provide a database of corresponding toxicological reactions as wel...

Intelligent gas sensing chip (I+NOSE) with ultra-low power consumption

Institute of Biomedical Engineering 2021/07/13

Integration of the sensing chip (I+NOSE) with readout circuitry as a dongle and demonstration of CO detection under H2 interference on the smart phone (Figure 1)
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This technique demonstrates a new gas sensor array (I+NOSE) not only compatible to the IC fabrication process but also provides several advantages over traditional MOS gas sensor. The most sensitive region of the silicon nanoelectronic devices on the gas sensor chip is to grow different gas sensor materials via ALD to form an array of gas sensors. Self-calibration of temperature, humidity and othe...

Label free CTC enrich biochip

Institute of Biomedical Engineering 2021/06/30

Sample processing workflow with the spiral microfluidic channels.
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Pleural effusion is very common and involves abnormal deposition of fluid in the pleural space. Malignant pleural effusion is the major cause of exudates in thoracentesis patients. Most cases of malignant pleural effusion are caused by lung cancer, breast cancer, and lymphoma; 15% of lung cancer patients will present with malignant pleural effusion initially, and up to 50% will have malignant pleu...

NYCU Physician-Engineer Module "Opening A New Peak" by Stan Shih

2021/04/23

NYCU established the Physician-Engineer Module last year. This year, the department receives support from the founder of Acer, Stan Shih, and the technology industry. A group of technology mentorship will be formed in NYCU.
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National Yang Ming Chiao Tung University, merged in February this year, became the first university in Taiwan with medical education research, technology training, and industry connection with abundant resources. Stan Shih, the founder of Acer and the alumni of NYCU, points out that Taiwan needs cross-domain leaders to lead the future of Taiwan. Therefore, the Physician-Engineer Module in NYCU tra...

Precise Live Caption in CDC Press Conference! Made in Taiwan for National Security Reason

2021/03/26

Online live broadcast of the Central Epidemic Command Center
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CDC press conference is sometimes delivered through live streaming. The captions below the streaming are extremely precise with real-time auto-correction, which has up to 92% accuracy and is invented by a team from Taiwan. A reporter Liu said that the screenshot is the daily CDC press conference which has precise captions since the end of last year. The AI-based captioning system is, in fact, ma...

The National Innovation Awards of Taiwan Government on the blood flow sensor

Institute of Electrical and Control Engineering 2020/12/01

National Innovation Award
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This program is designed to design a front-end analog circuit for a non-invasive, piezoresistive blood pressure sensing array with easy access to the data. The circuit has an automatic correction function. This is a self-correcting system for a sensor array designed for optimal array of pulse blood pressure sensor arrays, which is aligned with the signal between the sensors in the array sensor, co...

Self-charging ingestible polysaccharide battery coupled with a nanogenerator for controllable disinfection system

Institute of Biomedical Engineering 2020/09/22

Graphical abstract
  • GOOD HEALTH AND WELL-BEING AFFORDABLE AND CLEAN ENERGY

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Biomedical electronics plays a crucial role in bridging the gap between engineering and medicine by enabling the development of miniaturized medical equipment offering efficient diagnosis as well as treatment for various diseases. However, despite the recent advances in wearable biomedical devices, the key power source, the battery, is often toxic and hazardous to human beings as it can result in ...

3D stereo image reconstruction using Cyber-Physical sensing (CPS) for growth monitoring of the fruit tree – A case study of Syzygium samarangense tree

Institute of Electrical and Control Engineering 2020/09/10

Application of Cyber-Physical Sensing (CPS) 3D Stereo Modeling for Fruit Tree Growth Monitoring
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“3D stereo image reconstruction using Cyber-Physical sensing for growth monitoring of the fruit tree – A case study of Syzygium samarangense tree”, proposes that the several technology combination of Unmanned Aerial Vehicle (UAV), drone swarm, Real Time Kinematic(RTK), 3D image reconstruction, hyperspectrum and heterogeneous image fusion applied on the growth monitoring, analysis and modeling of t...

World's First Flexible Photoplethysmography (PPG) Sensor Patch, Facilitating Medical Big Data

2020/08/27

Successful research is derived from the focus on thousands of details, shared by Prof. Paul C.-P. Chao
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Recently, National Yang Ming Chiao Tung University (NYCU) has been integrating the resource from the NYCU Office of Research and Development and the GLORIA project by the Ministry of Science and Technology, Taiwan, fostering the industry-academia collaboration. NYCU provides a wide range of assistance for the collaboration, including application for patterns, promotion of technology licensing, and...

Tubular Energy Harvesters for Leadless Pacemakers

Institute of Electrical and Control Engineering 2020/08/01

Energy Harvesters
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Will be used to wrap around the cylindrical leadless pacemaker. The blood pressure causes the harvester on the pacemaker surface to deform and produce output electricity. The advantage of the new design is that the space inside the tubular harvester is not occupied by the energy conversion structures. Therefore, pulse generators can be integrated with the harvesters to reduce the volume and n...

The Development of Smart Contact Lens System for Glaucoma Diagnosis and Treatment

Institute of Electrical and Control Engineering 2020/07/20

The Development of Smart Contact Lens System for Glaucoma Diagnosis and Treatment
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High intraocular pressure is a common symptom in glaucoma patients, but the relationship between intraocular pressure and neurodegeneration is still unclear due to inconvenient measurement of intraocular pressure. The main treatment method for glaucoma patients is to place eye drops on the patients by themselves, which has a poor treatment effect. In order to solve the above problems, we will comb...

An Intelligent Driver Fatigue Monitor System with Emotion Recognition by Facial Action Unit Detection

Institute of Electrical and Control Engineering 2020/06/10

Value creation projects
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According to the report from World Health Organization (WHO), there are more than 1 million people die from the traffic accident every year. Most reasons of the accident are caused by the bad driving behavior due to the fatigue driving and the poor emotion status of the driver. In order to reduce these kinds of traffic accident, a Driver Monitoring System is the core idea in this research. By usin...

AI Help Preventing Epidemic! Face Mask detector Made by NYCU

2020/05/04

A team led by Prof. Wen-Huang Cheng (right) and Prof. Hon-Han Shuai (left) sees the need for epidemic prevention and develops a real-time face mask detector in two weeks using a camera.
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During the COVID-19 pandemic, Taiwan Centers for Disease Control (CDC) encourages the public to wear masks. Some crowded places, such as the MRT stations, campus, or commercial buildings, require massive human resources to monitor face masks. Acknowledging the disease control needs, Prof. Wen-Huang Cheng and Prof. Hong-Han Shuai work together on the "Large-Scale Face Mask Detecting System" to de...

Breath Ammonia Analyzer for CKD Screening/Monitoring

2019/12/19

Prof. Hsiao-Wen Zan' team of NYCU develops a biomedical breathing sensing system that can be used as rapid tests for high-risk people of chronic kidney disease and the evaluation of dialysis efficacy.
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Among the world, about 11% population has chronic kidney disease (CKD). In Taiwan, the increase rate of dialysis patients (end-stage of CKD) is the highest in the world. For dialysis patients, blood urea nitrogen (BUN) is the key parameter for doctor to determine the dialysis efficacy and the nutritional intake condition. However, through blood examination, BUN can not be obtained very frequently....

Dr. Lin Shien-Fong's laboratory won the National Innovation Award

Institute of Biomedical Engineering 2019/12/07

Award Photo
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Cerebrovascular diseases take away an average of over 10000 lives annually, even if patients with cerebral apoplexy survive, there are always sequelae caused by various degrees of nerve injuries leading to physical disability. What’s more, as muscular atrophy or functional degeneration occur easily to patients because of a long-time lack of exercises, they need to accept a long-term rehabilitation...

Dr. Lin Shien-Fong's laboratory won the Young Investigator Award of APHRS 2019 Thailand

Institute of Biomedical Engineering 2019/10/25

A. High efficiency of ChR2 expression in NRVM.
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Optogenetic, which is a novel and useful tool due to its unique ability to act on specific neuronal groups, has gained wide application in basic and clinical medical researches. It can manipulate different groups of specific neurons at the same time at the right location. Therefore, our novel objective of the study is to use optogenetics to specifically dissect the complex network of sympathetic a...

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